hrp0095p2-22 | Adrenals and HPA Axis | ESPE2022

Two Familial Cases of Congenital Adrenal Hyperplasia Combined or Complicated with Central Precocious Puberty

Markosyan Renata , Aghajanova Yelena

Central precocious puberty (CPP) may be secondary to congenital adrenal hyperplasia (CAH), due to 21-hydroxylase deficiency. CPP in CAH may be associated with elevated sex-steroid levels and possibly a decline in negative sex-steroid feedback after treatment initiation. We experienced the two family cases of the salt-wasting form of the CAH, complicated by CPP with early maturation of the hypothalamic-pituitary-gonadal axis in all patients from two families.<p class="abste...

hrp0094p2-49 | Adrenals and HPA Axis | ESPE2021

Assessment of Patients With Congenital Adrenal Hyperplasia in Armenia

Markosyan Renata , Navasardyan Lusine , Bayburdyan Gayane , Aghajanova Yelena ,

The congenital adrenal hyperplasias (CAH) comprise a family of autosomal recessive disorders that disrupt adrenal steroidogenesis.Aim: To investigate the clinical features of the patients with CAH.Methods: The current study was conducted on 106 Armenian patients with CAH.Results: Distribution between regions: 45.3% were from Yerevan, 13.2%-Syunik region, 11.3...

hrp0095p1-243 | Diabetes and Insulin | ESPE2022

Did Covid-19 pandemic restrictions impact on diabetic care of children and adolescents in Armenia?

Muradyan Irina , Aghajanova Yelena , Janvelyan Tamara , Markosyan Renata , Bayburdyan Gayane , Kalantaryan Lusine , Arakelyan Lusine , Navasardyan Lusine

Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disorder, which occurs mostly among children and adolescents. Armenia is a middle-low income country, where pediatric diabetic care is given centralized in three main centers. The 85-90% of diabetic children and adolescents are followed in the university hospital. During Covid-19 pandemic Armenia was under either lockdown or strict restrictions. The purpose of the current study is to assess the dynam...